Urbach-Wiethe disease is a rare genetic disorder that can cause calcification of brain tissue in the temporal lobes; this calcification can cause damage to the amygdalae.
The symptoms of the disease vary greatly from individual to individual.
They may include a hoarse voice, lesions and scarring on the skin, easily damaged skin with poor wound healing, dry, wrinkly skin, and beading of the papules around the eyelids.
(1994, 1995) investigated a patient suffering from Urbach–Wiethe (UW) syndrome, a very rare autosomal recessive disease, which produces bilateral calcifications in the anterior medial temporal lobes, especially of the amygdalae, in 50–75% of cases (Newton et al., 1971; Staut and Naidich, 1998).
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