In positional cloning, chromosome walking is used to identify clones that are progressively closer to a gene of interest.
What is positional cloning technique?
When it comes to finding the genetic variants that underlie the pathological emergence of diseases with straightforward Mendelian inheritance, positional cloning is the method of choice. It entails a series of sequential phases that are essential to the overall procedure, beginning with the identification of patients and the collecting of their DNA.
What is chromosome walking?
Chromosome walking is a method for cloning a gene (for example, a disease gene) from its known nearest markers (for example, a known gene), and it is employed with only minor alterations in cloning and sequencing efforts in plants, fungi, and animals.
Learn more about cloning technique: https://brainly.com/question/3549446
#SPJ4
