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Enzymes and chaperone proteins assist in protein folding that takes place after translation is complete.

What is Protein folding?

  • The physical process by which a linear polypeptide folds into its distinctive and useful three-dimensional shape is known as protein folding.
  • The solubility of the AA R-groups in water has a significant impact on how a polypeptide chain folds.
  • Protein folding occurs in four stages: primary, secondary, tertiary, and quarternary.
  • The secondary structure is the unfolding of the protein.
  • Amino acid chains are the building blocks of proteins, which fold into distinctive three-dimensional structures.
  • The final folded shapes of proteins are well-suited for their tasks and the bonds inside protein molecules assist stabilize their structure.
  • The subject of how a protein's amino acid sequence determines its three-dimensional atomic structure is known as the protein folding problem.
  • Around 1960, when the appeared, the idea of a folding "problem" first came into existence.

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