In conclusion, numerous animals have homologues of all human hepatitis viruses. The hepatitis B virus (HBV) is a small DNA virus with unusual features similar to retroviruses. It is a prototype virus of the Hepadnaviridae family.
With hundreds of millions of victims worldwide, viral hepatitis has become a serious issue for public health. Both acute infection and chronic sequelae, such as chronic active hepatitis and cirrhosis in the case of viral hepatitis B, C, and D, cause significant morbidity and mortality in the human population. Hepatitis B and, at least in some parts of the world, hepatitis C virus are strongly linked to hepatocellular carcinoma, one of the ten most prevalent malignancies globally.
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