Answer: After translation is complete, the newly synthesized protein must as fold into Its functional shape determined by some regions of the amino acid chain.
When protein folding into the mature, functional 3D state is complete, it is not necessarily the end of the protein maturation pathway
Explanation:
- Translation the polypeptide chain must fold to form a functional protein.
- For example, to function as an enzyme the polypeptide chain must fold correctly to produce a functional active site.
- In order to adopt a functional three-dimensional (3D) shape, the polypeptide chain must first form a series of smaller underlying structures called secondary structures.
- The polypeptide chain in these secondary structures then folds to produce the overall 3D tertiary structure.
- Once correctly folded, the protein can undergo further maturation through different post-translational modifications
- Post-translational modifications can alter the protein's ability to function, where it is located within the cell (e.g. cytoplasm or nucleus) and the protein's ability to interact with other proteins.
Hence conclusion is newly synthesized protein must fold into its functional shape.
A folded protein can still undergo further processing through post-translational modifications
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