The Preimplantation genetic diagnosis (PGD) is the technology that is used for the examination of embryonic DNA for the presence of disease causing alleles.
As the embryonic DNA came half from paternal and half from maternal side so there are chances that during the fertilization there may be some extra allele that may cause dysfunction or diseases in the embryonic DNA.
The examination of the embryo is necessary to check its allele before the implantation to avoid any further problems. This may also help to know if there are any genetic disorders in the embryonic DNA.
It uses a DNA probe to screen a cell removed from an embryo for disease-causing alleles.
Preimplantation genetic diagnosis (PGD) is used to check if there is a genetic disorder in embryonic DNA by checking alleles.
This is checked before the embryo has entered the uterus before implantation or before pregnancy has begun.
The Preimplantation genetic diagnosis (PGD) use two methodologies :-
FISH ( Fluorescent in situ hybridization)
PCR (Polymerase chain reaction)
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