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Abnormalities involve microtubules have been implicated in Alzheimer’s disease.

What are the Cytoskeletal Pathologies of Alzheimer Disease?

The extracellular amyloid plaques, which are primarily composed of the amyloid beta peptide, and the intracellular neurofibrillary tangles, which are composed of paired helical filaments of the microtubule-associated protein tau, are histopathological hallmarks of Alzheimer  disease.

Actin and the actin-binding protein cofilin have recently been implicated in other histopathological structures.

We present new findings about these cytoskeletal pathologies and emphasize how plaques, tangles, actin-containing inclusions, and their respective building blocks may contribute to Alzheimer pathogenesis and the disease's primary behavioral symptoms.

To learn more about Alzheimer’s Disease from the given link

https://brainly.com/question/18406872

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