In mitochondria, ATP synthase is a specialized ion channel,
In Neurons, sodium and potassium channels,
In muscle cells, calcium channels.
A channel blocker is the biological mechanism in which a particular molecule is used to prevent the opening of ion channels in order to produce a physiological response in a cell.
Channel blocking is conducted by different types of molecules, such as cations, anions, amino acids, and other chemicals.
Drugs bind to the extracellular regions of ion channels, causing the transmembrane opening to change in some way so as to allow specific ions to pass through.
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