If the solubility of sodium acetylsalicylate is roughly 120 g per 100 ml of water, then 5.9 mol/L of the saturated nac9h7o4 solution is used in the reaction.
Acetylsalicylic acid (trade name aspirin) is a well-known antipyretic and analgesic drug. Mixtures that benefit from the high solubility of sodium salt have been marketed for almost 90 years.
A novel crystalline form of sodium acetylsalicylate (aspirin sodium) is obtained by first precipitating aspirin sodium dihydrate in the crystalline form and then dehydrating it to anhydrous aspirin sodium.
Sodium aspirate can be prepared by adding excess pure acetylsalicylic acid to the sodium carbonate solution. Sodium hydroxide cannot be used as a base because it causes hydrolysis of acetylsalicylic acid to other products. Sodium acetylsalicylate is much more soluble in water than aspirin itself, so cooling the solution can cause excess aspirin to crystallize.
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