Question

DNA is composed of two strands, only one of which typically is used as a template for RNA synthesis. By what mechanism is the correct strand chosen

Answer 1

To choose the strand the promoter acts to aim the RNA polymerase.

What does RNA polymerase do?

RNA polymerase synthesizes RNA by following a strand of DNA. The primary transcription enzyme is RNA polymerase. When RNA polymerase connects to a promoter sequence near the start of a gene, transcription starts (directly or through helper proteins). To create a fresh, complementary RNA molecule, RNA polymerase employs one of the DNA strands (the template strand) as a template.

Three distinct RNA polymerases (RNAPs), which transcribe various kinds of genes, are present in all eukaryotes. RNA polymerase I transcribe rRNA genes, RNA polymerase II transcribes mRNA, miRNA, snRNA, and snoRNA genes, and RNA polymerase III transcribes tRNA and 5S rRNA genes.

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