The steps of phagocytosis in the correct order: B. Physical Contact A. Phagosome C. Digestion D. Phagolysosome E. Outflowing of Cytoplasm F. Excretion
Phagocytosis is a cellular process for ingesting and eliminating particles larger than 0.5 μm in diameter, including microorganisms, foreign substances, and apoptotic cells.An amoeba or other free-living single cell could make up the phagocyte, or it could be one of the body's cells like a white blood cell.
Chemotaxis
- movement in response to chemical stimulation
- pseudopods move toward microorganisms at the site of infection
Adherence
- attachment to a microbe
Ingestion
- engulfing pathogen with pseudopodia wrapping around pathogen
- pathogen is placed into a vesicle (phagosome) that contains lysozyme
Digestion
- phagosome maturation
- lysozyme merges w/phagosome>releases digestive enzymes>becomes a phagolysosome
- microbes are usually killed at this point
Elimination
- phagocytes eliminate the remaining pieces of microbe via exocytosis
- some components are saved to alert the immune system if the pathogen were to try and invade again.
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