Viruses that have reverse transcriptase are in the Group of Hepadnaviridae and Retroviridae.
Reverse transcription, also known as DNA synthesis from an RNA template, is carried out by the enzyme reverse transcriptase (RT). Reverse transcriptases are employed by eukaryotic cells to lengthen the telomeres at the ends of their linear chromosomes, viruses like HIV and hepatitis B to reproduce their genomes, and mobile genetic elements like retrotransposons to multiply inside the host genome.
A family of viruses is called Hepadnaviridae. Natural hosts include people, monkeys, and birds. Currently, there are 18 species in this family, spread across 5 genera.
Both the reverse transcription method, which enables the inclusion of these viruses into the family, and the genomic organization are the same as those of other members of the Retroviridae. Along with gag, pol, and env, two more genes (tas and bet) are expressed in cells.
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