Michael was recently diagnosed with a tumor of the pituitary gland and underwent surgery to remove the entire mass. After surgery the nurse noted that michael was producing an extremely large volume of urine. What might be causing michael to do this?.

Diabetes insipidus is a condition in which the affected person has the urge to pee a lot and feels thirsty all the time. Even though it is not directly related to diabetes, it is named as such because the affected person has symptoms similar to diabetes. The two main symptoms are polydipsia and polyuria.

Cause of Diabetes insipidus

Diabetes insipidus is caused by the lack of production of antidiuretic hormone (ADH). ADH is produced by the hypothalamus which then gets stored in the pituitary gland. When the person was subjected to surgery to remove the entire mass of cancer cells in the pituitary gland, the ability of the gland to store ADH could have been lost.

The ADH allows the retention of water by concentrating the urine. In a person with diabetes insipidus, the production of AHD is affected, and in very rare cases the response by the kidneys to ADH is reduced which also reduces the water reabsorption and increases urine volume.

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