A crossover design is a reiterated assessments design in which each experimental unit (patient) receives various treatments at different time periods, i.e., the patients switch from one therapy to another during the trial.
What is the advantage of a crossover design?
The crossover design has the benefit of each subject acting as his or her own control, and it requires a lesser number of patients than parallel-group trials.
There are various drawbacks. For example, crossover designs often last longer than parallel-group research.
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