Question

This table shows the codons found in messenger RNA. Using this information, what sequence of nucleotides in the template strand of DNA could code for the polypeptide sequence Phe-
Ser-Gln?

Answer 1

The sequence of nucleotides in the template strand of DNA could code for the polypeptide sequence Phe-Ser-Gln will be AAA, TGT, and GTC.

What are polypeptides?

Polypeptides are macromolecules which are formed from chains of amino acids linked together by peptide bonds.

The amino acids in polypeptides are coded for in mRNA by a triplet of nucleotides known as codons.

mRNA is synthesized from a template DNA strand based on complementarity.

The codons that code for the given amino acids in an mRNA follow the genetic code and are as follows:

• Phe = UUU
• Ser = UCU
• Gln = CAG

In DNA uracil is replaced by thymine.

Therefore, the sequence of nucleotides in the template strand of DNA could code for the polypeptide sequence Phe-Ser-Gln will be AAA, TGT, and GTC.

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Answer 2

The sequence of nucleotides in the template strand of DNA could code for the polypeptide sequence Phe-Ser-Gln is AAG, AGG, and GUU.

What are Nucleotides?

Nucleotides may be defined as a molecule that consists of a nitrogen-containing base, a phosphate group, and a pentose sugar.

The codons that codes for the given amino acids are as follows:

• Phe = UUC
• Ser = UCC
• Gln = CAA.

Therefore, The sequence of nucleotides in the template strand of DNA could code for the polypeptide sequence Phe-Ser-Gln is AAG, AGG, and GUU.

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