The neuromuscular junction and the neurotransmitters involved in muscle contraction are motor neuron and acetylcholine respectively
Mechanism of muscle contraction
The mechanism of muscle contraction involve:
- Motor neuron first sends action potential to the muscle
- Acetylcholine (ACh) is then released from vesicles on motor neuron
- Acetylcholine binds to receptors on muscle membrane and activates second action potential on the muscle
- The action potential opens active transport pumps of sarcoplasmic reticulum
- Calcium ion floods the sarcoplasm
- Calcium ion attaches to troponin thereby changing its shape.
- This change in shape pulls tropomyosin away from the myosin-binding sites on actin
- ATP attaches itself to the myosin cross-bridge
- ATP on myosin head and in the presence of Mg+ splits ATP into ADP+ P which energizes the myosin head allowing the muscle to swing forward
- The myosin head then binds to actin
Therefore, the neuromuscular junction and the neurotransmitters involved in muscle contraction are motor neuron and acetylcholine respectively
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