Explain and illustrate the mechanism of muscle contraction. Refer to the "all or none" response, neuromuscular junction and the neurotransmitters involved.​

Respuesta :

The neuromuscular junction and the neurotransmitters involved in muscle contraction are motor neuron and acetylcholine respectively​

Mechanism of muscle contraction

The mechanism of muscle contraction involve:

  • Motor neuron first sends action potential to the muscle
  • Acetylcholine (ACh) is then released from vesicles on motor neuron
  • Acetylcholine binds to receptors on muscle membrane and activates second action potential on the muscle
  • The action potential opens active transport pumps of sarcoplasmic reticulum
  • Calcium ion floods the sarcoplasm
  • Calcium ion attaches to troponin thereby changing its shape.
  • This change in shape pulls tropomyosin away from  the myosin-binding sites on actin
  • ATP attaches itself to the myosin cross-bridge
  • ATP on myosin head and in the presence of Mg+ splits ATP into ADP+ P which energizes the myosin head allowing the muscle to swing forward
  • The myosin head then binds to actin

Therefore, the neuromuscular junction and the neurotransmitters involved in muscle contraction are motor neuron and acetylcholine respectively​

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