The low level of the acetylcholinesterase enzyme, the nurse should anticipate what effect of this state is to accumulation of acetylcholine in the synaptic cleft resulting in over-stimulation of nicotinic and muscarinic acetylcholine receptors and hinder neurotransmission.
Acetylcholinesterase is a cholinergic enzyme primarily present at postsynaptic neuromuscular junctions, mainly in muscles and nerves. It spontaneously breaks down or hydrolyzes acetylcholine, a naturally occurring neurotransmitter, into acetic acid and choline.
The typical symptoms of acute poisoning are agitation, muscle weakness, muscle fasciculations, hypersalivation, sweating.
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