Question

Manny is using a computer model to investigate the effects of substitution mutations. The model presents manny with a long base sequence for a gene. Manny then selects one base for a mutation, such as by substituting cytosine, "c", for adenine, "a". Manny completes many trials of mutations. In most trials, the result of the substitution mutation is either no effect, or a polypeptide in which one amino acid is altered. In one trial, however, the result is a truncated polypeptide. Many of its terminal amino acids are missing. What is the most likely explanation for the truncated polypeptide

Answer 1

The truncated polypeptide results in the computer simulations performed by Manny can be found with the alteration in the gene structure and the formation of the stop codon in between the chain sequence.

What is truncated polypeptide?

The truncated polypeptide is the sequence of the amino acid that is modified in a way to enable the formation of the tertiary and the quaternary structure of the protein.

The truncation in the polypeptide chain can be attained with the alteration in the gene structure. The attempts of Manny to perform the substitution mutation may result in the change in the cytosine nucleotide at the C or the N terminal of the polypeptide chain.

This results in the formation of the termination in the elongation with the stop codon, and thereby forms the truncated polypeptide.

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