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The ISA is run by some set of instructions. This instructions are;

1.  Arithmetic: This Instructions perform various Arithmetic functions

2. Logical:  This instruction often carryout Logical operations on one or more operands.

3. Data transfer: This handles the transfer of instructions from memory to the processor registers and then backward process again.

4. Flow control: These instructions helps in breaking the sequential flow of instructions and jumping to instructions at different locations.  

Instruction set is simply known to be a full combination /number of instructions that are understood by a CPU.

It is know as a machine code that is often written in binary, and shown by assembly language.

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