In the experiment by Nirenberg and Matthaei described in the animation, why does it make biological sense that the U2 oligonucleotide showed such poor ability to bind to ribosomes and tRNA charged with phenylalanine

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We have that for the Question "In the experiment by Nirenberg and Matthaei described in the animation, why does it make biological sense that the U2 oligonucleotide showed such poor ability to bind to ribosomes and tRNA charged with phenylalanine"

Answer:

  • This is because, the genetic code could not involve a two-base codon because such a system would not provide enough unique codons to cover all 20 amino acids.  

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