in the epiphyseal plate, the microscopic zone in which chondrocytes undergo rapid cell division and become aligned into longitudinal columns of flattened lacunae is called the:

Respuesta :

In the epiphyseal plate, the microscopic zone in which chondrocytes undergo rapid cell division and become aligned into longitudinal columns of flattened lacunae is called the: zone of proliferating cartilage.

Longitudinal growth of long bones is carried out by the endochondral ossification process.

This process consists of the proliferation, hypertrophy and apoptosis of chondrocytes with vascular invasion and mineralization of the cartilaginous matrix.

In the epiphyseal plate, the proliferation cartilage zone is contiguous with the reserve cartilage zone in the direction of the diaphysis.

In this area the chondrocytes undergo mitosis, forming axial isogenic groups and organizing themselves in well-defined longitudinal columns.  

As a consequence of this active mitosis, the layer thickens and the entire plaque grows longitudinally.

In this microscopic zone, cells are larger than the reserve zone and actively synthesize collagen (type II and XI) and other cartilaginous matrix proteins.

Therefore, we can conclude that the zone of proliferating cartilage is where chondrocytes undergo rapid cell division and become aligned into longitudinal columns of flattened lacunae.

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