The fact that no one comes to visit or check on Gregor after his transformation suggests that Gregor was just as lonely and isolated before his transformation as after. Considering that Gregor no longer leaves his home, it’s surprising that he doesn’t have any friends check on him. The only people outside the family to check on him are an official from work and the maid. This lack of visitors shows that Gregor is actually somewhat used to the isolation and loneliness he experiences after his transformation