Question

Approximately how many mutations occur naturally in DNA per 10,000 bases?
A. 2
B. 2000
C. 200
D. 20

Answer 1

Explanation:

Modern methods indicate that the mutation rate is roughly one to two mutation per 10,000 genes per generation.

Answer 2

In human cells, approximately TWO (2) MUTATIONS occur naturally in DNA per 10,000 bases (Option A is correct).

• The mutation rate (u) refers to the occurrence of new mutations in a given nucleotide sequence over time.

• In human cells, the mutation rate is approximately 10⁻⁴ per generation.

• Therefore, in a DNA sequence that has 10,000 base pairs of length, this value is equal to 2 mutations per generation (u = 2 / 10,000 = 10⁻⁴).  

In conclusion, approximately 2 MUTATIONS occur naturally in DNA per 10,000 bases (Option A is correct).

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