Question

Which of the following describe(s) the role of cytotoxic T cells in the specific immune response?
I. They kill cancer cells.
II. They kill cells infected by viruses.
III. They interact with MHC-I molecules
A.II only
B.II and III only
C.I and II only
D.I and III only
E.I, II, and III

Answer 1

E. Sounds like all e are the same  E.I, II, and III

Answer 2

Answer: Option E is the correct answer

Explanation:

T cells are part of the adaptive immune system and have a large repertoire of receptors that allow their activation or inhibition. T lymphocytes or T cells have the ability to recognize and lyse (kill) infected or transformed cells; these transform cells could include cancer or tumor cells. This recognition is due to the contact of the T cell receptors (principally the T cell receptor) with the Major Histocompatibility Complex molecule I (also known as MHC I). When cells are infected or are transformed, the expression of these MHC I molecules are altered, and therefore it is detected by T cells as something “abnormal” and therefore release molecules that cause cell death, such as perforin, granzymes, IFN-γ and the Tumor Necrosis Factor-α. Therefore, T cells can kill cancer or infected cells and interact with MHC-I molecules.