3. Define the term zwitterion. Draw the structure of alanine and explain why this molecule is a
zwitterion in certain conditions.

Respuesta :

Answer:

A zwitterion or a hybrid ion is an ion that has both a positive and negative charge and can act as either a base or an acid.

Explanation:

A zwitterion or a hybrid ion is an ion that has both a positive and negative charge and can act as either a base or an acid. The net charge on a zwitterion is zero since it has equal number of positive and negative charges.

Alanine, is a monoamino monocarboxylica acid that is diprotic when fully protonated. The carboxylic acid group, COOH and the amino group, NH₃⁺, are able to produce one proton each. At a pH equal to the isoelectric point of alanine, it exists mainly in the zwitterionic form with the α-amino group protonated as NH₃⁺ and the α-carboxyl group deprotonated as COO⁻ . This is because at the isoelectric point of alanine (6.0), pI is greater than the acid dissociation constant, pKa of the α-carboxyl group whereas, pI is less than the acid dissociation constant, pKa of the α-amino group, so the two groups are negatively and positively charged respectively.

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