Question

Which of the following molecules is synthesized at specific times during the cell cycle and
forms an active complex with a kinase?

A)PDGF
B)MPF
C)Cdk
D)cyclin

Answer 1

Answer:

D. Cyclin

Explanation:

Cyclins drive the events of the cell cycle by partnering with a family of enzymes called the cyclin-dependent kinases (Cdks). A lone Cdk is inactive, but the binding of a cyclin activates it, making it a functional enzyme and allowing it to modify target proteins.

Answer 2

Cyclin is synthesized at specific times during the cell cycle and forms an active complex with a kinase.

The phases of the cell cycle are directed by a highly complex and finely regulated protein interaction network.

Among these proteins, the phosphorylating enzymes called cyclin-dependent kinases (CDKs) and their activating subunits the cyclins (A, B, D and E) stand out.

• The cyclin-dependent kinases undergo phosphorylation on their amino acids (serines and threonines).

• The cyclins (so called because they appear and disappear throughout the cycle), bind to the CDKs and control their phosphorylation reactions.

• The cyclic assembly between these two compounds, cyclins and CDKs, their activation and disassembly are the central processes that direct the cell cycle.

Therefore, we can conclude that cyclin is synthesized at specific times during the cell cycle and forms an active complex with a kinase..

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