Question

what does headache mean in Spanish what

Answer 1

Headache means "dolor de cabeza" in Spanish.

Answer 2

Simple....

what does headache mean in Spanish?

Well, translated---->>>

Un dolor de cabeza.

That^^^^means A headache.

If you would like you use it in a sentence you could say: Me duele la cabeza. (My head hurts)

Thus, your answer.