The correct answer to this open question is the following.
Although there are no options attached, we can say the following.
The changes that the Roman Empire experienced in the fourth century CE completely changed the way the Roman Empire was ruled. The causes of these changes were the following.
Roman Emperor Constantine was persecuting Christians and sent them into the Colosseum to be devoured by the lions. But one night, he had a dream. An angel sent from the heavens told him to adopt Christianity in the empire and he would have fortune and success on the battlefield.
That is why Emperor Constantine proclaimed Catholicism as the official religion in the Roman Empire. Later, Constantine decided to move the capital of the Roman Empire to Constantinople (modern-day Istambul, Turkey). This new location was an important cosmopolitan city, with ports that served to increase trade and connect to other parts of the ancient world.