Answer:
Correct answer is find a water route to the Pacific.
Explanation:
First option is the correct one as it refers to expedition that started after United States took Louisiana. President Jefferson wanted Lewis and Clark to research the west territories, so they could be appointed to United States, and that is why one of the goals was to reach Pacific Ocean.
Other options are not correct, as they didn't search for Natives, and especially a route for Canada.
Removal of Natives was not a part of this expedition at all.
