Question

what is the start codon and its importance to the reading frame?

what is the consequence of changing CTC to CTT in the DNA template strand?

what is the consequence of changing CTC to CAC in the DNA template strand? (note: this is the point mutation that causes the sickle cell disease)

Answer 1

Answer:

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Answer 2

The start codon is AUG, which is the first codon of an mRNA transcript translated by a ribosome. Normal hemoglobin would be produced by the cell with the CTT mutation if CTC was changed to CTT. A DNA codon mutation from CTC to CAC changes the encoded amino acid from leucine to histidine, resulting in sickle cell hemoglobin.

What are codons?

A codon is a three-nucleotide set of DNA or RNA that forms a unit of genomic information encoding a specific amino acid or signaling the end of protein synthesis.

The start codon is AUG, which is the first codon of an mRNA transcript translated by a ribosome.

Normal hemoglobin would be produced by the cell with the CTT mutation if CTC was changed to CTT.

A DNA codon mutation from CTC to CAC changes the encoded amino acid from leucine to histidine, resulting in sickle cell hemoglobin.

Thus, the above-mentioned are the consequences of the given scenarios.

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