Question

Cyclic AMP phosphodiesterase is an enzyme that catalyzes the conversion of cyclic AMP to a different molecule. Which of the following best predicts the effect of inhibiting cyclic AMP phosphodiesterase in a muscle cell stimulated by epinephrine?

The concentration of cyclic AMP will decrease because adenylyl cyclase will no longer be activated.

The G protein will diffuse out of the cell because it will no longer bind to the plasma membrane.

Phosphorylase kinase will remain active because protein kinase A will no longer be deactivated.

Glycolysis will stop because epinephrine signaling will no longer stimulate glycogen breakdown.

Answer 1

Answer:

Phosphorylase kinase will remain active because protein kinase A will no longer be deactivated.

Explanation:

Phosphodiesterase is an enzyme that has the function of hydrolyzing cAMP by converting it to AMP. As a result, a protein called kinase is inactivated and lipids break down in fat metabolizing cells. CAMP is a cellular messenger.  Cyclic AMP phosphodiesterase, in turn, is an enzyme that catalyzes the conversion of cyclic AMP into a different molecule. as a result, a molecule called kinase A is deactivated. However, if inhibition of cyclic phosphodiesterase AMP in a muscle cell stimulated by adrenaline, Kinase A will not be deactivated, so phosphorylase kinase will remain active.