Answer:
Hybrid incompatibility has a genetic basis both in plants and animals
Explanation:
In plants, hybrid incompatibility may be associated with different factors including, for example, mismatch recognition in chromosomal pairing, changes in the ploidy level, homozygous lethal alleles, epigenetic-associated factors, postzygotic hybrid incompatibility, etc.
Hybrid incompatibility is recognized to promote reproductive isolating barriers between species, thereby understanding into the genetic basis of this phenomenon may result useful to understand the evolutionary forces that are associated with speciation.
You can reverse the hybrid incompatibility by changing the ploidy level, since it ensures a correct chromosome pairing during the cell division. You can use colchicine, it is an antimitotic agent that is widely used to duplicate the ploidy level.