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Which of the following substances is most likely to be soluble in water?
A. a polar substance capable of forming hydrogen bonds
B. a molecule with hydrophilic heads and hydrophobic tails
C. a hydrophobic substance
D. a nonpolar substance

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Answer:

a

Explanation:

A polar substance which can participate in hydrogen bonding is most soluble in water.

What is a polar substance?

  • Polar substances have molecules where there is a high difference in electronegativity between their constituent atoms
  • For example, Hydrochloric acid (HCl) is a polar substance
  • Polar substances are "water-loving" which means they dissolve easily in water

To identify the most water-soluble molecule, we need to understand hydrogen bonding and solubility in water.

What is hydrogen bonding?

  • This form of bonding occurs when there is an attractive electrostatic force between an electronegative group and a hydrogen atom bonded to an electronegative group
  • For example, there is hydrogen bonding among water molecules.

What kind of a molecule is water?

  • Water is a polar molecule
  • It has electronegative oxygen and electropositive hydrogen
  • By the concept of "like dissolves like", water dissolves polar substances best
  • Molecules that form hydrogen bonds in water also dissolve very well

Thus, a polar substance that can form hydrogen bonds will be most soluble in water. Hydrophobic substances and non-polar substances cannot dissolve well in water.

Learn more about hydrogen bonding here:

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