Question

The researcher performed a follow-up experiment to measure the rate of oxygen consumption by muscle and brain cells. Predict the effect of the MT - ND5 mutation on the rate of oxygen consumption in muscle and brain cells. Justify your prediction. The researcher had hypothesized that the addition of the vitamin that is similar in structure to NADH would increase the activity of the mutated NADH dehydrogenase enzyme in individuals with the disorder. Explain how the vitamin most likely increased the activity of the enzyme.

Answer 1

Answer:

The rate of oxygen consumption by muscle and brain cells will decrease. The MT-ND5 mutation causes a buildup of lactic acid which occurs as a result of glycolysis not entering the Krebs cycle and instead entering fermentation. Because it is not entering the krebs cycle, there is no oxygen being consumed.

Explanation: