Answer:
The most important change that Renaissance brought was that humanism became the central ideology in the arts and the sciences.
Humanism is the idea that humans are at the center of the universe (in a figurative sense). Humanism promotes a new appreciation of the human body, mind, and promotes self-development among people.
Renaissance artists such as Michelangelo and Leonardo Da Vinci completed works that highlighted what they believed was the most perfect human possible, the ideal humans should aspire to.
Humanism made theocentrism, or the idea that God is the center of the unverse, less strong, and promoted new developments in philosophy, and later on science, that resulted in great advancements in later decades.