Answer: North-eastern Africa + Near East. A space between Egypt and Mesopotamia. First civilizations were born there, it was there were (probably) agricultural revolution started, where first writing were invented. The first civilized people we are able to identify there are Sumerians and pre-Sumerians (in spite of that we do not know many things about them).
Explanation: territories of today´s Egypt, Izrael, Palestine, Lebanon, Syria, Jordania, Iraq and partly Turkey.
