In humans, XO individuals are females with Turner's syndrome and XXY individuals are males with Klinefelter syndrome. Which of the following events may not give rise to a Klinefelter male?

A. Nondisjunction at meiosis I in the father.
B. Nondisjunction at meiosis II in the father
C. Nondisjunction at meiosis I in the mother.
D. Nondisjunction at meiosis II in the mother.

Respuesta :

Answer:

The correct answer is "C"

Explanation:

Klinefelter's disorder, XXY guys, can happen because of non-dis-junction of X chromosomes during pro-phase of meiosis I in females.  

One of the eggs from such a meiosis could get both X chromosomes, and the other would get no X chromosomes.  

On the off chance that these eggs are hence prepared with typical sperm, different sex chromosome aneuploidies could happen:  

XXY - clean male who may have some female body qualities, and at times expanded learning obstacles.  

XXX - There are no genuine stigmata associated with this disorder. Ladies with triple X as a rule are fruitful.  

XO - clean female with short stature, with low mental capacity, inability to experience pubescence (Turner's disorder).  

YO - Non-feasible; qualities on X chromosome required for advancement and endurance.  

Non-dis-junction during sperm creation can likewise bring about aneuploidy of sex chromosomes.

The correct option is options A and C.

  • Chromosomal aneuploidy:

Chromosomal aneuploidy is a genetic condition in which an individual has either an abnormal number of one or more chromosomes or has pieces of chromosomes lacking or in excess.

  • Klinefelter's syndrome:

Klinefelter's syndrome, XXY males, can occur due to the nondisjunction of X chromosomes during the prophase of meiosis I.

If an egg cell with an extra X chromosome (XX) is fertilized by a sperm cell with one Y chromosome, the resulting child will have Klinefelter syndrome.

Similarly, if a sperm cell with both an X chromosome and a Y chromosome (XY) fertilizes an egg cell with a single X chromosome, the resulting child will have Klinefelter syndrome.

Hence, option (A) and (C) is correct.

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