Answer:
During presentation of APC-bound antigen, macrophages and dendritic cells secrete the cytokine, interleukin-1, that activates T helper cells
Explanation:
Macrophages interact with T cells in order to generate T cell activation in target organs, and are themselves activated by inflammatory messenger molecules (cytokines) produced by the T cells.
Macrophages produce toxic chemicals, such as nitric oxide, that can kill surrounding cells.
During presentation of APC-bound antigen, macrophages and dendritic cells secrete the cytokine, interleukin-1, that activates T helper cells