Metastatic cancer cells:___________ a) have lost their adhesion to the extracellular matrix, freeing them from the original tumor. b) are able to leave the tumor where they originated and travel to distant locations to begin new tumors at distant sites. c) only need to cross a single layer of capillary endothelial cells to form tumors at distant sites. d) all of these choices are correct. e) become malignant when they grow rapidly.
