Respuesta :
Answer:
- axonemal microtubules: (G) is in cilia and flagella
- nucleation: (H) formation of tubulin oligomers
- treadmilling: (R) assembly and disassembly on opposite ends of the same filament
- desmin: (T) keeps muscle myofibrils in register
- EB1: (I) binds to microtubule plus ends
- ARP2/3 complexes: (P) nucleates actin filament branches
- myosin subfragment 1 (S1): (O) decorates actin filaments
- tropomodulin: (J) prevents loss of subunits from filament minus ends
- gelsolin: (S) breaks and caps actin filaments
- microvilli: (N) increase cell surface
- filamin: (K) connects crisscrossing actin filaments into 3D networks
- phosphoinositides: (L) binds to profilin and CapZ
- MAPs: (F) stabilizes and organizes microtubles
- plectin: (C) crosslinks microtubles to intermediate filaments
- lamin: (E) forms scaffold underlying nuclear envelope.
Explanation:
- Axonemal microtuble: an axoneme is a microbule based cytoskeleton structure of a eukaryotic cilium or flagellum. It provides motility, and also gives support to the structure.
- nucleation: it is a process where interaction of several tubulin molecules lead to the formation of microtubules seed. This process occurs spontaneously in purified tubulin solutions.
- treadmilling: is a phenomenon, that especially occurs in actin filaments and microtubules,where continuous removal of actin monomers from pointed ends of filament occur and their reincorporation at the other ends
- desmin: it is a specific protein found in muscle that integrates sarcolemma, Z disk and nuclear membrane in sarcomeres and regulates sarcomere architecture
- EB1: its a plus-end tracking protein that binds to plus end of microtules and modulates their dynamics and interactions with intercellular organelles.
- ARP2/3 complex: its a seven-subunit central actin nucleator that binds to the side of filament to promote new filament growth as a branch thus forming a complex actin network.
- myosin subfragmnet (S1): S1 is the head fragment of myosin globular heads, that contains the ATPase and actin-binding activities of myosin.
- tropomodulin: it is a protein that binds and caps the pointed ends(or minus ends) of actin filaments thereby regulating its length in muscle cells as well as non muscle cell.
- gelsolin: is an actin binding protein that binds and caps actin filament(responsible for assembling and disassembling of filaments)
- microvilli: found in the apical surface of epithelial cells or the stereocillia, spine like protrusions, that increase the cell surface area for diffusion upto 100 times.
- filamin: is an actin binding protein that holds two filaments at large angles.
- phosphoinositides: it regulates the activities of many actin binding proteins and have the tendency to bind with profilin and CapZ(its a capping protein that caps the barbed ends of actin filament)
- MAPs: microtubules associated protein or MAPs binds to and stabilizes microtubules lattice. MAPs have repeating domains that allow eash MAP molecule to associate with more than one tubulin dimer.
- plectin: a structural protein of the cytoskeleton that maintains tissue integrity
- lamin: are fibrous protein of type V intermediate filaments that provide structural function and transcriptional regulation in the cell nucleus.
