Active transport moves substances against the concentration gradient. is a major difference between facilitated diffusion and active transport
Explanation:
One of the comparisons is that both facilitated diffusion and active transport utilize proteins as their medians of moving their materials to and from the cell. Another relationship is the primary purpose of both facilitated diffusion and active transport is to drive material over the cell membrane.
One of the variations is that active transport demands energy, while facilitated diffusion does not require energy. The energy that active transport uses is ATP. The Major difference is that facilitated diffusion enables substances to accompany the concentration gradient either way, while active transport only has substances go one way, against their concentration gradient.