Why might the drug orlistat, which blocks pancreatic lipase, helps an individual lose weight? View Available Hint(s) Why might the drug orlistat, which blocks pancreatic lipase, helps an individual lose weight? Pancreatic lipase catalyzes the reaction that breaks the remaining polysaccharides into oligosaccharides but not into individual sugars, blocking them from being absorbed, potentially leading to weight loss. If pancreatic lipase is blocked, fat-soluble vitamins will not be capable of being absorbed by diffusion in the small intestines, potentially leading to weight loss. Blocking pancreatic lipase will, in turn,, block the chemical digestion and absorption of lipids, potentially leading to weight loss. Pancreatic lipase is responsible for slowing down the body's overall metabolic rate. By blocking pancreatic lipase, the body will increase in metabolic activity, which potentially could lead to weight loss.
