Answer: Major depressive disorder
Explanation:
When someone has been consistently stressed intensively for a long period of time, they may start to have a major depressive disorder.
Major depressive disorder is a depression that affect someone's life severely in a way that it changes their mood and how they do things such that they start to lose appetite and have a lack of sleep. A person starts to lack an interest in things they used to enjoy doing and struggle functioning normal on daily activities.
They give up on life and feel like it's over and nothing is worth it.