Well, my 5 reasons would be:
The risk factor. The risk of nuclear power would be INSANE, if we had nukes packed in the backs of our cars and got in a car crash, let's just say we wouldn't have roads after that accident.
Nuclear waste. The waste caused by nuclear is outrageous, it stays for hundreds of thousands of years, and we already dump 2,000 metric tons of nuclear waste per year already, if we had a community based on nuclear, it'd be terrible.
The cost would be tremendous, you would have to build tons of sites, hire probably a new military just for it, scientists, everything would make the cost tremendous.
The foreign risk. Think of all the people who walk into America ( terrorists ) and say "Imma' go blast myself a couple o' Americans". Terrorists would have even more reasons to raid areas for Uranium for the money or to build a bomb, if we got one hit with all the plants we would need, it'd probably cause a very large chain reaction destroying part of our country.
Nuclear radiation. If we have nuclear everything everywhere, how are we gonna protect ourselves from the radiation? We gonna go to work in hazmat suits?
Those are my five reasons, hope it helps, if not, comment below please!!!!