Question

How can a tumor suppressor gene lose its function? Check all that apply
a. Duplication
b. Aneuploidy leading to loss of the tumor suppressor gene
c. Aberrant DNA methylation
d. Gene mutation

Answer 1

Option d. Gene mutation

Explanation:

Antioncogenes also called as tumor suppressor genes. The cell proliferation is controlled negatively by tumor suppressor genes. Antioncogenes maintains the replication and division process of cell. The antioncogenes prevent uncontrollable growth of cell. The mutation in the gene can lead to cancer.

The gene mutation can cause tumor suppressor gene to lose its function. The mutation in the tumor suppressor genes will code for certain proteins with loss of function in tumor suppression.

Learn more: Tumor suppressor genes

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