Question

A silent mutation
A. would likely not affect the activity of a protein.
B. is the result of a change in a codon for an amino acid in a protein to a stop codon.
C. results in a protein that is truncated from the N terminal end.
D. would not affect the primary structure of a protein.
E. results in a shorter mRNA transcript of the gene.

Answer 1

A & D

A silent mutation is usually a substitution mutation that causes a change in a codon that codes for the same amino acid as the initial codon.

Explanation:

This is possible because just 20 amino acids are coded for by 64 codons. An example is Leucine that is coded by 4 codons; GAA, GAG, GAT, and GAC. If you look closely, a substitution mutation of the last nucleotide of the codon will less probably cause a change in the translated amino acid. These mutation are therefore non-lethal.

Learn More:

For more on silent mutations check out;

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