Question

The BRCA-1 genes in humans encode proteins that have role in maintaining DNA stability. Mutation in this gene results in formation of non-functional protein, which is not able to repair damaged DNA, resulting in a significantly increased risk of breast cancer. BRCA-1 is a/an:?

Answer 1

Answer:

tumor supressor gene.

Explanation:

BRCA1 (breast cancer 1) is a human tumor suppressor gene, that regulates cell cycle and abnormal proliferation. The protein BRCA1, produced by this gene, is part of the DNA damage detection and reparation. Some mutations of this gene are implied with cancer, specially breast cancer. Women with mutations on this gene have an increased 51-95% risk of breast cancer and 22-66% ovary cancer cumulative to the age of 70 years old.