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Answer:
Sub-optimal test sensitivity, false negative results are common, especially when influenza activity is high
Sensitivity of RIDTs to detect influenza B viral antigens is lower than for detection of influenza A viral antigens.
Although specificity is high, false positive results can also occur, especially during times when influenza activity is low.
Some RIDTs distinguish between influenza A or B viruses while others do not. RIDTs that provide results on the type of influenza virus (e.g., influenza A or B virus), do not provide information on influenza A virus subtype [e.g., A(H1N1)pdm09 versus A(H3N2)] or specific virus strain information (e.g., degree of similarity to vaccine strains). RIDTs cannot distinguish between seasonal influenza A virus infection and novel influenza A virus infection (due to infection with avian or variant influenza A viruses).
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