Answer:
It led to an attack by Native Americans on early settlers.
Explanation:
St. Louis location gave it advantage to become a major base for inter regional trade. It had connection through Ohio river and Missouri to the east and west whereas Mississippi to the north and south. Due to this reason, the population in St. Louis began to increase.
The native people were not pleased with the inflow of immigrants due to their tribal emotional reasons. This led the Native people to attack the early settlers. In such way, the establishment of the Fort St. Lewis caused issues in early Texas history.
