Answer:
The correct answer is A.
Explanation:
Grade A of recommendation is defined when there is good, strong evidence that the practice involved has a benefit on the patients.
To stablish that there is good, strong evidence, a well conducted clinical trial is necessary. This means that the clinical trial should be randomized and the sample under study must be representative of the population of patients.
The grade A of recommendation encourage physicians to offer or provide the service/treatment to their patients if they match the criteria.